Research Areas

RESEARCH AREAS

Ø Asymmetric Synthesis
Ø Domino Reactions
Ø Arene Functionalizations
Ø Green Protocols in Organic Synthesis
Ø Carbohydrate Research
Ø Antibacterial Activity Studies

RESEARCH HIGHLIGHTS

1. The group has developed various asymmetric organocatalysts from naturally available proline and derivatives of camphor- 10-sulfonic acid and glucosamines. The catalytic activity of these organocatalysts has been investigated in various asymmetric transformations.

2. Novel sugar derivatives were synthesized.

3. Developed green protocols for the synthesis of an array of heterocycles under solvent-free and catalyst-free conditions. Synthesized several vesicular acetylcholine transporter inhibitors.

4. Highly unstable o-benzoquinone monoimines were chemically generated for the synthesis of hitherto unknown 1,4-benzoxazine derivatives.

5. A plethora of halogenated bicyclo[2.2.2]octenones were synthesized.

ONGOING PROJECTS

1. Novel Methodologies for the Generation of o-Benzoquinone Monoimides: Synthesis of 1,4-Benzoxazine Derivatives.
   CSIR, Oct 2009 - Sept. 2012.

2. Microwave Heating Technology: A Green Chemistry Approach for Functiona-lization of Arenes.
     MHRD, May 2010 - Apr. 2013.

3. Domino Reactions and Asymmetric Synthesis
     DST, May 2012 - Apr. 2015

RESEARCH FACILITIES

The research group is well equipped with basic facilities to perform reactions for organic synthesis/ asymmetric synthesis. Laboratory has facilities to carry out reactions under inert atmosphere and at low temperatures up to -90 oC. It also procured HPLC instrument along with chiral columns.

In addition, instruments such as FT-IR, UV-Vis, GC, GC-MS, HRMS, CHN analyzer, etc., are available in the Department and 500 MHz NMR and XRD instruments are available in the Institute Instrumentation Centre.